Interestingly, subjects with lower vitamin D status at baseline responded more efficiently to supplementation than those with more adequate status. The recommended dietary intake of 15 microg is adequate to maintain the S-25-OHD concentration around 40-55 nmol/L during winter, but if the optimal S-25-OHD is higher than that even higher vitamin D intakes are needed. Browse our wide selection of Vitamins for Delivery or Drive Up. S-iPTH tended to decrease in those with highest dose response to supplementation.Ī clear dose response was noted in S-25-OHD to different doses of vitamin D3. Shop Signature Care Vitamin D3 50mcg Dietary Supplement Softgel - 400 Count from Jewel-Osco. The dose-response to supplementation decreased with increasing vitamin D status at baseline, r = -0.513, p = 0.002. Equilibrium in S-25-OHD concentration was reached in all groups after 6 weeks of supplementation at 57.7 (8.9) nmol/L, 59.9 (8.9) nmol/L and 70.9 (8.9) nmol/L in the groups with increasing vitamin D supplementation. The S-25-OHD concentration increased significantly (p < 0.001) in all supplemented groups, whereas it decreased in the placebo group by 8.3 (13.2) nmol/L. Calciotropic variables were assessed from serum and urine samples. Vitamin D3 50 mcg (2000 IU) Chewable Vanilla Flavor, 120 Tablets 8.29 Add to cart Vitamin D3 125 mcg (5000 IU) Drops Lemon Flavor, 1. Fasting morning blood was drawn at the beginning of the study, and thereafter every second week. Vitamin D3 25 mcg plays a role in the maintenance of calcium and phosphorus levels in the blood. The women were randomly assigned into one of four groups receiving 0 (placebo), 5, 10 or 20 microg of vitamin D3 daily for 12 weeks. We also studied which dose would be efficient in decreasing S-iPTH concentration in these subjects.įorty-nine 65- to 85-year-old women participated. Secondly to determine the smallest efficient dose to maintain serum 25-OHD concentration above the insufficiency level. Supports Strong Bones Immune System Support Supports A Positive Mood For additional formula information, view the Supplement Facts panel. Cholecalciferol, otherwise known as D3, is the vitamin D that is formed when the sun touches human skin. We studied how serum 25-hydroxy vitamin D (S-25-OHD) concentrations respond to different doses of vitamin D3 supplementation. Vitamin D3 provide 50 mcg of cholecalciferol per tablet. Typically, insufficiency is accompanied with high intact parathyroid hormone, (S-iPTH) concentrations. To permanently change your account setting, go to My Account. Get vitamin D3 at iHerb today Your preference has been updated for this session. This insufficiency results from an inadequate amount of sunshine and a low dietary intake of vitamin D. Vitamin D3 helps absorb calcium to strengthen bones, and reduces inflammation and pain while boosting mood and immune health. Vitamin D insufficiency poses a problem in many parts of the world, the elderly being an especially vulnerable group.
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